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Molecular structures of PIM1 and PIM7. Copyright permission obtained... Download Scientific

The Proviral Integration of Molony murine leukemia virus (PIM)-1 protein contributes to the solid cancers and hematologic malignancies, cell growth, proliferation, differentiation, migration, and other life activities. Many studies have related these functions to its molecular structure, subcellular localization and expression level. However, recognition of specific active sites and their.

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Figure 1 from PIM 1 kinase as a target for cancer therapy Semantic Scholar

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Previously, we reported that PRL directly stimulated rapid expression of the protooncogene, pim-1, at the mRNA and protein levels in lactogen-dependent Nb2-11 cells. In the present study, experiments were conducted to evaluate signaling mechanisms by which PRL regulates transcription of pim-1. Toward this end, a 1,268-bp segment upstream of the.

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Carbon molecular sieve membranes (CMSMs) commonly lose permeability over time due to the collapse of micropores. This decline in permeability, due to the densification of the membrane, is known as physical aging. CMSMs derived from polymers of intrinsic microporosity (PIM-1) are highly affected by physical aging, with declines in permeability greater than 60% over time. It is hypothesized that.

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PIM-1 nanoparticles were synthesized using an anti-solvent precipitation method,res as reported previously [8]. To fabricate nanoparticulate films, a volume of 5 μL (4 mg mL −1) of PIM-1 solution (corresponding to 20 μg PIM-1) was dropped onto the graphene foam electrode and dried at room temperature. Dense films were obtained by deposition.

PIM1 mixed matrix membranes for gas separations using costeffective hypercrosslinked

PIM1. Proto-oncogene serine/threonine-protein kinase Pim-1 is an enzyme that in humans is encoded by the PIM1 gene. [5] [6] [7] Pim-1 is a proto-oncogene which encodes for the serine/threonine kinase of the same name. The pim-1 oncogene was first described in relation to murine T-cell lymphomas, as it was the locus most frequently activated by.

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PIM-1/holey graphene oxide (GO) mixed matrix membranes (MMMs) have been prepared and their gas separation performance for CO 2 /CH 4 mixtures assessed. Nanopores have been created in the basal plane of gas-impermeable GO by chemical etching reactions, and the resulting holey flakes have been further chemically functionalized, either with octadecylamine (ODA) or with PIM-1 moieties, to aid.

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In this study, we present the fabrication of fibers with tunable morphology and porosity from an intrinsically microporous polymer, PIM-1, using a simple one-step electrospinning technique. The method involves the dissolution of PIM-1 in a good solvent tetrahydrofuran (THF) and cosolvents composed of THF and a nonsolvent, either dimethylformamide (DMF) or toluene, for electrospinning without.

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PIM-1 incorporated with beta-cyclodextrin (β-CD) were prepared by Chung's group [100], as shown in Fig. 7 b. The unique 3-dimensional (3D) hollow bowl structure of β-CD endowed the obtained MMMs with 162% higher CO 2 permeability with slight sacrifice of 1% for CO 2 /N 2 selectivity and 2% for CO 2 /CH 4 selectivity, and physical aging.

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